- "We have unleashed a wolf upon this world, and if we do not act, he will consume us all."
- ―Giuliano Della Rovere
Giuliano Della Rovere is a powerful cardinal in the church, and one of Rodrigo Borgia's greatest rivals.
The rich and powerful Cardinal Della Rovere is Rodrigo Borgia's chief rival for the papacy. When he loses, he devotes himself to unseating the Pope, whom he sees as lewd, blasphemous, and his vast moral inferior. But Della Rovere becomes so obsessed with his quest that he ends up stooping to the Borgias' level and beyond to achieve his goal.
|Season one appearances|
|The Poisoned Chalice||The Assassin||The Moor|
|Lucrezia's Wedding||The Borgias in Love||The French King|
|Death, on a Pale Horse||The Art of War||Nessuno (Nobody)|
|Season two appearances|
|The Borgia Bull||Paolo||The Beautiful Deception||Stray Dogs||The Choice|
|Day of Ashes||The Siege at Forli||Truth and Lies||World of Wonders||The Confession|
|Season three appearances|
|The Face of Death||The Purge||Siblings||The Banquet of Chestnuts||The Wolf and the Lamb|
|Relics||Lucrezia's Gambit||Tears of Blood||The Gunpowder Plot||The Prince|